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Synthon 公司于1991 年創(chuàng )辦于荷蘭,集科研、開(kāi)發(fā)和生產(chǎn)于一體。
兩年后該公司推出了第一個(gè)仿制藥品多巴酚丁胺,2003 年推出辛伐他汀獲熱銷(xiāo)。該公司在巴塞羅納和圣洛倫索擁有工廠(chǎng),為歐洲市場(chǎng)生產(chǎn)40余種藥品?;钚猿煞钟山菘斯埠蛧桶⒏⑸a(chǎn),劑型則在西班牙配制。這些藥品在西班牙或美國包裝,整個(gè)流程都在Synthon 公司的質(zhì)量控制下。
2004年Synthon 公司在美國推出了甲磺酸帕羅西汀制劑Pexeva?,用于治療抑郁癥。使用鹽酸帕羅西汀Paxil?的GlaxoSmithKline 公司對此提出了訴訟,已于12 月份裁定。Synthon 公司還獲得批準銷(xiāo)售抗抑郁藥fluvoxamine(LuvoxTM),但尚未上市。
2007 年,該公司宣布完全放棄在美國生產(chǎn)品牌藥的計劃,而將重點(diǎn)放在現有的仿制藥業(yè)務(wù)上。
Synthon, with headquarters in Nijmegen, the Netherlands is an international pharmaceutical company and a leader in the field of generic medicines. Synthon has been working in biotechnology since 2007 and is developing rapidly into a specialty pharmaceutical company, focusing on the therapeutic areas of auto-immune diseases – particularly multiple sclerosis - and oncology. Our products are currently approved by regulatory agencies in over 80 countries worldwide and marketed through strategic partnerships and – in dedicated areas – through direct sales. Synthon employs about 1,400 staff worldwide, and in 2011 it recorded a turnover of EUR 260 million.